Nicotinamide mononucleotide (NMN) is a well-known and studied substance that naturally occurs in the body.
The precursor for NAD (Nicotinamide Adenine Dinucleotide) which is a protein that is found in every cell of the body. It is believed to slow down the process of aging.
Nucleotides are the basis of NMN. Nucleotides can play various roles in the human body, for instance, they are an element of DNA.
A variety of proteins and enzymes require NAD to fulfill their tasks such as the repair and maintenance of DNA.
NAD is a source of energy for the body, which aids in to repair and growth and is possibly crucial in slowing the process of aging.
NMN Benefits
Research indicates that decreased energy levels are among the main reasons for the process of aging.
Increased NMN intake can boost levels of NAD which provides body cells with more energy.
The use of NMN supplements to boost NAD levels offers several advantages:
Enhances brain function
The brain needs a sufficient amount of nutrients and oxygen in order to function. The research suggests that NMN supplementation can improve brain functioning by increasing the flow of blood to the brain.
Enhances the muscle’s function
Muscles are unable to grow and regenerate due to aging.
NMN could be able to reverse these issues and boost the endurance and strength of muscles.
Helps improve heart health
NMN has been proven to prevent the development of heart disease in rodents through the reduction of scarring, which is a key reason for heart failure.
It aids in treatment for cancer
The benefits of NMN in the treatment of cancer is in two ways:
The use of NMN immunotherapy in rodents has been proven to boost the effectiveness of various therapies employed in the treatment of cancer
Reduces the adverse consequences of chemotherapy including cognitive impairment and damage to the heart (as observed in mice)
Prevents diabetes and obesity
Mitochondria, cell organelles, transform the food we consume into energy. They are therefore crucial for metabolism as well as the growth of metabolic diseases.
The increased NMN levels have been proven to boost the number of mitochondria found in livers of obese mice. This can help protect them from the effects of obesity.
NMN is also believed to boost the health and metabolism of mice born to overweight mothers.
A study conducted in 2020 on mice revealed that NMN can reverse the effects of diet and age-related diabetes, and also stop kidney disease and neurodegeneration linked to diabetes.
Improves eye function
In the absence of NAD causes rapid degeneration of nerves that provide the eye. This can increase the risk of loss of vision.
In the event that NMN is replenished by our bodies, it stops degeneration of the eye nerves.
A study found that NMN could help protect cells in the eye and decrease inflammation in patients suffering from dry eye disease.
Enhances fertility in women
Age-related decline can lead to problems with fertility for women. NMN has been found to increase age-related decline in egg count and quality in female mice.
Promotes DNA repair
DNA codes can be damaged when we get older. Repairing DNA damage is a way to prevent diseases that are a result of aging.
NAD helps to support enzymes known as sirtuins which are the protectors of our health. Sirtuins play a crucial role in the repair of DNA.
Sirtuins are also able to regulate telomere length Another sign of the aging process.
Research has shown how feeding mice NMN triggers sirtuins.
NMN also fixes DNA damage that can occur from radiation and age.
NAD in comparison to. NMN: What’s The difference?
NMN can be described as the source to NAD. The quantity of NAD depends on the NMN present in the body.
NAD is an enzyme, and plays two main roles:
Regulates cell function
Transforms food into energy
NAD is also involved in all essential functions that cells perform and also affects wake and sleep cycles neuro-health, sleep and the health of vital organs.
NAD levels NAD decrease as we the aging process. Stress on the body or mind reduces NAD levels.
The low levels of NAD increase your risk of developing health conditions such as type 2 diabetes Alzheimer’s and heart disease.
The two NMN along with NAD are both required to generate energy within the body.
Some of the differences among NAD and NMN are:
NMN is more readily in the bloodstream and is more easily
NAD might have a greater influence on mental health
MNM has a greater impact on physical health
NAD Benefits
NAD offers numerous health benefits, including:
Ageing slows down
Maintain cognitive function and protect memory
Increase the energy levels
Lower blood pressure
Lower levels of blood cholesterol
Reduce cancer risk
NMN Benefits: Anti-aging
NAD levels decline as we age, and can trigger the process of aging. It’s involved in repair building, repairing DNA, and protecting it from harm.
NAD is often referred to as the “fountain of youth’ since it is believed to stop the negative effects caused by aging on the cell level.
The most effective method to increase NAD amounts is by increasing consumption of NMN.
How Can You Naturally Increase the NMN?
NMN supplements are a popular way to boost its levels in blood.
It can be found in some food sources, including
Avocados
Cabbage
Tomatoes
Raw beef
Broccoli
The small amounts of NMN can also be found in cow milk, cucumbers and edamame.
NMN is readily absorbed by the digestive. But, more information is required to know how an increase in NMN intake can increase NAD levels in blood.
Are NMN Supplements safe?
Nicotinamide mononucleotide is a safe drug. There aren’t any adverse effects observed in humans to date.
What are the adverse effects of NMN?
A study over time of NMN effects in rodents showed no adverse reactions or toxicity.
The study on NMN in humans indicates no concerns about safety after a single orally administered doses of 100, 200, or 500 mg were administered.
There were no changes in heart rates or blood pressure or blood oxygen levels body temperature, blood pressure changes or sleep issues were detected.
Summary: NMN Benefits
Nicotinamide mononucleotide (NMN) is a naturally occurring substance that is found in every cell of the human body.
NMN serves as the precursor to NAD which is a molecule needed by proteins and enzymes that are involved in the maintenance and repair of DNA.
NMN provides many benefits, including increasing the muscle and brain function and promoting heart health as well as preventing weight gain and diabetes.
NAD along with NMN are used for anti-aging therapies.
Insufficient concentrations NAD are associated with a lower risk of developing conditions. NAD increase the risk of developing diseases such as Alzheimer’s disease, diabetes, and heart disease.